Abstract： Objective To practice and evaluate T2DM screening in children and adolescents with high blood pressure and aged 10 to 18 years with the protocol based on the clinical practice recommendations(ADA 2008).Methods General population from Changping District of Beijing was taken for stratified random sampling,accessing 3719 schoolchildren aged 10 to 18 years.Those who met one of the following conditions were taken for fasting blood glucose screening:(1)overweight/obesity:BMI >85th percentile for the age-sex stratification;(2)high blood pressure:a blood pressure≥ 90th percentile for age-sex stratification.Subjects with fasting blood glucose≥ 5.6 mmol/l were then taken for OGTT.Results The final diagnosis rate was 0.98/1000 for DM and 30.3/1000 for IFG.Of the IFG subjects,51.6% had both overweight/obesity and high blood pressure,6.5% had overweight/obesity and 41.9% had isolated high blood pressure without overweight/obesity.If not screening glucose of children and adolescents with isolated high blood pressure,near half of the patients with IFG would be missed.Conclusions It is very necessary to test glucose homeostasis in children and adolescents with high blood pressure