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Change of serum retlnol binding protein-4 level and its clinical significance in patients with obesity and impaired glucose regulation
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- Author:
- No author available
- Journal Title:
- CHINESE JOURNAL OF DIABETES
- Issue:
- 7
- DOI:
- 10.3321/j.issn:1006-6187.2008.07.006
- Key Word:
- 视黄醇结合蛋白4;糖调节受损;胰岛素抵抗;Retinol binding protein-4;Impaired glucose regulation; Insulin resistance
Abstract： Objective To assay serum retinol binding protein-4(RBP-4) levels in subjects with overweight or obesity(OW/Ob) and impaired glucose regulation(IGR), and to explore the correlation between RBP-4 and insulin resistance. Methods RBP-4 were determined by ELISA in 52 NGT and 58 IGR patients. Results RBP-4 was correlated with WC, WHR,HOMA-IR,TG,FBG (r=0.289,0.322,0.377,0.41,0.432,all P<0.01).FBG,TG,WHR were independent influencing factors for RBP-4 (r2=0.186,0.305,0.340 respectively). Conclusions RBP-4 is increased in subjects with OW/Ob or IGR and correlated with FPG,TG and WHR
- [1]吴海娅,贾伟平,魏丽,等.肥胖及2型糖尿病患者血清视黄醇结合蛋白4水平的变化及其临床意义[J].2006,(3).
- [2]杨治芳,毛季萍.性激素与内脏型肥胖及胰岛素抵抗[J].2004,(z1).
- [3]J.Denis McGarry.Banting lecture 2001 dysregulation of fatty acid metabolism in the etiology of type 2 diabetes[J].2002,51(1).
- [4]Jang Y,Shin MJ,Lee JH,etc.Serum retinol binding protein 4 levels are associated with serum adiponectin levels in non-diabetic, non-obese subjects with hypercholesterolemia.[J].2007,378(1).
- [5]Graham TE,Yang Q,Bluher M,etc.Retinol-binding protein 4 and insulin resistance in lean, obese, and diabetic subjects.[J].2006,354(24).