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The relation of peripheral leukocyte counts with urinary albumin in patients with type 2 diabetes

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Author:
No author available
Journal Title:
CHINESE JOURNAL OF DIABETES
Issue:
1
DOI:
10.3321/j.issn:1006-6187.2008.01.006
Key Word:
白细胞;2型糖尿病;尿白蛋白;Urinary albumin

Abstract: Objective To investigate the relation of peripheral leukocyte total and its differential counts with urinary albumin(UAlb)in patients with type 2 diabetes.Methods The 564 subjects with type 2 diabetes were stratified according to UAER levels.The total and differential leukocyte counts of peripheral blood were measured.Demographic and potential metabolic confounding factors were analyzed with multiple correlation and logistic regressions to evaluate the effects of leukocyte counts on UAER.Results With the increase of UAER,the peripheral total leukocyte,neutrophil,monocyte,eosinophil and basophil counts increased.In contrast,the lymphocyte count decreased.The differences persisted even after adjusting the influence of age,sex,duration of diabetes and other known risk factors.Conclusions Our study shows that peripheral leukocyte counts,even within the normal range,are related with UAlb in subjects with type 2 diabetes in a dose-dependent manner.

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