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The study on the mRNA expressions of adiponectin and tumor necrosis factor alphal and on their relation with insulin resistance in omental adipose tissue of obese subjects

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Author:
No author available
Journal Title:
CHINESE JOURNAL OF DIABETES
Issue:
1
DOI:
10.3321/j.issn:1006-6187.2008.01.005
Key Word:
脂联素;肿瘤坏死因子;肥胖症;Obesity

Abstract: The study of omental adipose tissue of patients with obesity(n=19)and without obesity(n=24)showed that the expression of adiponectin(APN)gene was significantly lower in obesity subjects than in non-obesity subjects and the expression of TNF-α gene was significantly higher in obesity than in non-obesity.There was negative correlation between the expressions of APN and TNF-α gene in obesity subjects.The obesity and insulin resistance were the independent influencing factors for the expressions of APN and TNF-α gene.

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