Vitamin D deficiency induces the impairment of glucose metabolism in mouse

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ZHANG Zeng-li()
LI Bing-yan()
WANG Xiao-hun()
Journal Title:
Volume 15, Issue 12, 2007
Key Word:


  • [1]Freemark M,Avril I,Fleenor D,et al.Targeted deletion of the PRL receptor:effects on islet development,insulin production,and glucose tolerance.Endocrinology,2002,143:1378-1385.
  • [2]Carvalho-Filho MA,Ueno M,Carvalheira JB,et al.Targeted disruption of iNOS prevents LPS-induced S-nitrosation of IRbeta/IRS-1 and Akt and insulin resistance in muscle of mice.Am J Physiol Endocrinol Metab,2006,291:E476-E482.
  • [3]Panda DK,Miao D,Tremblay ML,et al.Targeted ablation of the 25-hydroxyvitamin D 1 alpha-hydroxylase enzyme:evidence for skeletal,reproductive,and immune dysfunction.Proc Natl Acad Sci U S A,2001,98:7498-7503.
  • [4]张增利,李冰燕,史勇,等.1α羟化酶活性和血钙水平对24羟化酶基因表达的影响.中国应用生理杂志,2006,22:339-342.
  • [5]Giarratana N,Penna G,Amuchastegui S,et al.A vitamin D analog down-regulates proinflammatory chemokine production by pancreatic islets inhibiting T cell recruitment and type 1 diabetes development.J Immunol,2004,173:2280-2287.
  • [6]Schlumbohm C,Harmeyer J.Hypocalcemia reduces insulin turnover but not insulin-mediated glucose metabolism in piglets.Acta Diabetol,2002,39:191-202.
  • [7]Chiu KC,Chu A,Go VL,et al.Hypovitaminosis D is associated with insulin resistance and beta cell dysfunction.Am J Clin Nutr,2004,79:820-825.
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