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Survey of peripheral arterial disease and analysis of its risk factors in hospitalized diabetic patients
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- Author:
- No author available
- Journal Title:
- CHINESE JOURNAL OF DIABETES
- Issue:
- 11
- DOI:
- 10.3321/j.issn:1006-6187.2007.11.002
- Key Word:
- 糖尿病;踝肱指数;外周动脉病变
Abstract： 目的 通过踝肱指数(ABI)检查,探讨住院糖尿病患者下肢外周动脉病变(PAD)的患病率,并分析影响ABI的危险因素.方法 纳入华西医院内分泌科2004年8月～2006年12月住院糖尿病患者665例,使用多普勒血管超声仪检测ABI,同时检测血小板、血脂、尿酸、HbA1c和纤维蛋白原(Fib)等;通过回归分析探讨影响ABI的危险因素.结果 665例糖尿病患者中,ABI降低组(ABI＜0.9)107例(16.1%);ABI升高组(ABI≥1.3)51例(7.7%);ABI及PBI均正常者(0.9≤ABI＜1.3)516例(76.2%).与ABI正常者相比,ABI降低组患者年龄更大,病程更长,收缩压、血尿酸、TC、LDL-C、血小板、Fib更高;多因素logistic逐步回归分析显示年龄、血小板数和Fib水平是导致ABI降低的独立危险因素;而病程和LDL-C是导致ABI升高的危险因素.结论 通过ABI检测发现,大约23.8%的住院糖尿病患者存在PAD;合并糖尿病PAD的患者血压、血脂以及尿酸代谢紊乱更为明显,且合并血液高凝状态.因此,对门诊和住院糖尿病患者,应常规进行ABI检测以早期发现糖尿病PAD;严格控制血压、血脂、尿酸以及改善高凝状态对于预防糖尿病PAD至关重要.
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