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The comparison of mRNA expressions of adiponectin, tumour necrosis factor alphal and peroxisomal proliferator-activated receptorγ2 between male and female in human abdominal subcutaneous and omental adipose tissue
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- Author:
- No author available
- Journal Title:
- CHINESE JOURNAL OF DIABETES
- Issue:
- 10
- DOI:
- 10.3321/j.issn:1006-6187.2007.10.005
- Key Word:
- 脂联素;肿瘤坏死因子-α;过氧化物酶体增殖物激活受体(PPAR)γ2;性别
Abstract： 目的 比较男女腹部皮下脂肪组织、网膜脂肪组织中脂联素、肿瘤坏死因子-α(TNF-α)、过氧化物酶体增殖物激活受体γ2(PPARγ2)mRNA表达.方法 选择30例择期外科手术患者,男15例,女15例,用RT-PCR法检测腹部皮下脂肪组织和网膜脂肪组织中脂联素、TNF-α、PPARγ2 mRNA表达.结果 (1)男性皮下脂肪组织中脂联素mRNA显著低于女性,网膜脂肪组织中TNF-αmRNA显著高于女性(均P＜0.05).(2)女性皮下脂肪组织中脂联素mRNA表达高于其网膜脂肪组织,男女网膜脂肪组织中TNF-αmRNA均高于各自的皮下脂肪组织(P＜0.05～0.01).(3)男女间皮下脂肪组织和网膜脂肪组织中PPARγ2 mRNA表达差异无统计学意义(P＞0.05).结论 人腹部皮下脂肪组织和网膜脂肪组织中脂联素、TNF-αmRNA的表达可能存在性别差异,而PPAγ2mRNA表达的性别差异则不明显.
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