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β3-adrenoreceptor Trp64Arg polymorphism in diabetic peripheral neuropathy
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- Author:
- No author available
- Journal Title:
- CHINESE JOURNAL OF DIABETES
- Issue:
- 9
- DOI:
- 10.3321/j.issn:1006-6187.2007.09.006
- Key Word:
- 糖尿病,2型;β3肾上腺素能受体;周围神经病变;多态现象,基因学
Abstract： 研究对象为2型糖尿病(T2DM)合并周围神经病变组(43例)、T2DM无周围神经病变组(66例)和健康对照组(54例).测定3组β3肾上腺素能受体(β3-AR)基因型,并记录临床指标.结果显示β3-AR基因多态性与肥胖、胰岛素抵抗有关,与DM周围神经病变无关.
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