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Association of angiopoietin-2 in vitreous with diabetic vitreous hemorrhage
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- Author:
- No author available
- Journal Title:
- CHINESE JOURNAL OF DIABETES
- Issue:
- 7
- DOI:
- 10.3321/j.issn:1006-6187.2007.07.003
- Key Word:
- 糖尿病视网膜病变,增生型;血管生成素2;玻璃体出血
Abstract： 目的 探讨血管生成素2(Ang-2)与糖尿病玻璃体出血的相关性.方法 用ELISA法分别检测糖尿病玻璃体出血患者31例和非糖尿病视网膜脱离患者25例玻璃体和血浆Ang-2浓度.统计分析玻璃体Ang-2浓度、血浆Ang-2浓度、血压、血脂、FPG及HbA1c等指标与糖尿病玻璃体出血的关系.结果 糖尿病玻璃体出血患者玻璃体Ang-2浓度(中位数:3765 ng/L)较非糖尿病视网膜脱离组(274 ng/L)显著升高(P＜0.05),糖尿病组玻璃体Ang-2浓度(3765 ng/L)高于同组患者血浆Ang-2浓度(2716 ng/L).以行玻璃体切除术患者为整体,是否糖尿病玻璃体出血为因变量进行logistic回归分析,玻璃体Ang-2浓度和HbA1c水平进入回归方程.结论 玻璃体Ang-2浓度升高是糖尿病玻璃体出血的重要独立危险因素之一.
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