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Differentiation of rabbit marrow stroma cells into insulin-producing cells

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Author:
No author available
Journal Title:
CHINESE JOURNAL OF DIABETES
Issue:
5
DOI:
10.3321/j.issn:1006-6187.2007.05.019
Key Word:
骨髓细胞;胰岛素分泌细胞;基因表达调控;细胞分化

Abstract: 目的 探讨将骨髓基质细胞(MSCs)诱导成为胰岛素分泌细胞(IPCs)的方法.方法 体外培养新西兰兔骨髓及胰腺基质细胞和SD大鼠胰腺基质细胞,利用含有胰腺基质细胞培养基的混合培养基诱导培养MSCs.结果 以兔及SD大鼠胰腺基质细胞培养基均可诱导兔MSCs生成IPCs.结论 兔及SD大鼠的胰腺基质细胞培养基均可将兔MSCs诱导分化为IPCs.

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