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Effects of intensive insulin therapy on the GH/IGF-Ⅰ axis of the critically ill rats with diabetes and scald
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- Author:
- No author available
- Journal Title:
- CHINESE JOURNAL OF DIABETES
- Issue:
- 4
- DOI:
- 10.3321/j.issn:1006-6187.2007.04.019
- Key Word:
- 糖尿病;胰岛素强化治疗;生长激素;胰岛素样生长因子1
Abstract： 本实验将30只糖尿病烫伤大鼠随机分为胰岛素强化治疗组和常规治疗组,测定各组血清生长激素(GH)和胰岛素样生长因子Ⅰ(IGF-Ⅰ)浓度,并观察死亡率.结果表明,胰岛素强化治疗使血糖控制在3.9～5.6 mmo1/L,能明显改善糖尿病烫伤大鼠GH-IGF-Ⅰ轴紊乱,并显著降低死亡率.
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