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The expression of CD11b/CD18 of polymonphonuclear (PMN) leukocytes of peripheral blood is elevated in early diabetic nephropathy
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- Author:
- No author available
- Journal Title:
- CHINESE JOURNAL OF DIABETES
- Issue:
- 2
- DOI:
- 10.3321/j.issn:1006-6187.2007.02.010
- Key Word:
- 糖尿病肾病;CD11b/CD18;中性白细胞
Abstract： 观测86例2型糖尿病(T2DM)患者CD11b/CD18的表达,分析其与24 h尿白蛋白排泄量(UAE)及TNF-α的关系.T2DM患者多形核嗜中性白细胞(PMN)CD11b/CD18表达高于正常人;伴有大量白蛋白尿的T2DM患者外周多形核白细胞CD11b/CD18表达高于伴微量白蛋白尿或正常白蛋白尿的T2DM患者;T2DM患者外周血PMN白细胞CD11b/CD18表达与促炎症介质TNF-α浓度正相关,与24 h UAE正相关.
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