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Analysis of insulin sensitivity in patients with polycystic ovary syndrome and its association with correlative factors
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- Author:
- No author available
- Journal Title:
- CHINESE JOURNAL OF DIABETES
- Issue:
- 2
- DOI:
- 10.3321/j.issn:1006-6187.2007.02.003
- Key Word:
- 多囊卵巢综合征;钳制技术;胰岛素敏感性
Abstract： 目的 测定多囊卵巢综合征(PCOS)患者的胰岛素敏感性(IS),并分析其相关影响因素.方法 将观察对象分为PCOS肥胖组(10例)、PCOS非肥胖组(28例)和正常对照组(9例),IS用两步法高胰岛素-正葡萄糖钳夹技术评估.结果 (1)PCOS两组患者的葡萄糖利用率M值明显低于对照组(P均＜0.01),肥胖的PCOS患者M值降低更明显.(2)多元线性回归分析显示游离睾酮及BMI与M值负相关(P＜0.05).结论 非肥胖和肥胖PCOS患者均存在明显的胰岛素抵抗,PCOS患者IS与游离睾酮及BMI密切相关.
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