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Therapeutic effect observation of avandia combined with glimepiride and metformin in treatment of type 2 diabetes
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- Author:
- No author available
- Journal Title:
- CHINESE JOURNAL OF DIABETES
- Issue:
- 1
- DOI:
- 10.3321/j.issn:1006-6187.2007.01.005
- Key Word:
- 糖尿病,2型;胰岛素抵抗;罗格列酮
Abstract： 目的 观察马来酸罗格列酮(RSG)对2型糖尿病(T2DM)患者的疗效和安全性. 方法 128例T2DM患者随机分为RSG组(66例)及对照(Con)组(62例),观察治疗前后空腹及餐后2小时血糖(FPG,2 hPG)、糖化血红蛋白(HbA1c)及胰岛素(Ins)的变化. 结果 连续服RSG 3个月后,其FPG、2 hPG、HbA1c及FIns与试验前比较差异均有统计学意义(P＜0.05);与Con组比较差异也有统计学意义(P＜0.05);对肝肾功能等无影响. 结论 RSG能显著降低血糖并改善胰岛素的敏感性,本研究尚未发现其明显不良影响.
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