The evaluation of the risks of cardio-and cerebro-vascular events associated with metabolic syndrome in the cohort aged over 40 years in Huayang community of Shanghai by the different MS diagnostic criteria

( views:167, downloads:0 )
Author:
()
()
()
()
()
()
()
Journal Title:
CHINESE JOURNAL OF DIABETES
Issue:
Volume 12, Issue 03, 2004
DOI:
Key Word:

Abstract: Objective To compare the risk of incidence of cardiovascular events associated with the metabolic syndrome defined by WHO(1999) and NCEP ATPⅢ(2001) and to explore an available diagnostic definition of MS in China, and to assess its value on the prediction of cardiovascular events Methods A total of 971 subjects aged over 40 years with a follow up of 5 years in Huayang community of Shanghai were included The metabolic syndrom predicted cardiovascular risks were compared among the four MS definitions of the WHO(1999), ATPⅢ(2001), Chinese suggested definition Ⅰ and Ⅱ Results The relative risks(RR) of cardiovascular events associated with the metabolic syndrome using WHO(1999) and ATPⅢ(2001) definitions were 3 92 and 2 66 respectively Using Chinese suggested definition Ⅰ and Ⅱ, the RR of cardiovascular events associated with the metabolic syndrome were 6 59 and 5 43 respectively and the RR of stroke were 2 61 and 2 44 Conclusion Among four definitions of the metabolic syndrome(WHO,ATPⅢ, Chinese suggested definition Ⅰ and Ⅱ ), Chinese suggested definition Ⅰ predicts the risk of cardiovascular events most strongly In addition, the Chinese suggested definition Ⅰ is more simple, practical and easy to popularize

  • [1]Wilson PW, Kannel WB, Sibershatz H, et al. Clustering of metabolic factors and coronary heart disease. Arch Intern Med,1999, 159: 1104-1109.
  • [2]Isomaa B, Almgren P, Tuomi T, et al. Cardiovascular morbidity and mortality associated with the metabolic syndrome. Diabetes Care,2001, 24: 683-689.
  • [3]Ridker PM, Burning JE, Cook NR, et al. C-reactive protein,the metabolic syndrome, and risk of incident cardiovascular events. An 8-year follow-up of 14719 initially healthy American women. Circulation,2003, 107: 391-397.
  • [4]World Health Organization. Definition, diagnosis and classification of diabetes mellitus and its complications. Report of a WHO consultation, Part 1: Diagnosis and classification of diabetes mellitus. WHO: Geneva, 1999.
  • [5]National Institutes of Health: Third report of the national cholesterol education program expert panel on detection, evaluation,and treatment of high blood cholesterol in adults (Adult treatment Panel Ⅲ ). Executive summary. Bethesda, MD, National Institutes of Health, National Heart, Lung and Blood Institute,2001 (NIH publ. no. 01-3670).
  • [6]Ford ES, Giles WH. A comparison of the prevalence of the metabolic syndrome using two proposed definitions. Diabetes Care,2003, 26: 575-581.
  • [7]贾伟平,项坤三,陈蕾,等.两种代谢综合征工作定义在上海地区人群中应用的比较.中华医学杂志,2004,84:534-538.
  • [8]贾伟平.肥胖及糖尿病防治中值得高度重视的问题.上海医学,2003,26:1-2.
  • [9]陈蕾,贾伟平,陆俊茜,等.上海市成人代谢综合征流行调查.中华心血管病杂志,2003,31:909-912.
WanfangData CO.,Ltd All Rights Reserved
About WanfangData | Contact US
Healthcare Department, Fuxing Road NO.15, Haidian District Beijing, 100038 P.R.China
Tel:+86-010-58882616 Fax:+86-010-58882615 Email:yiyao@wanfangdata.com.cn