Effects of puerar in injection on diabetic peripheral neuropathy

( views:150, downloads:0 )
Author:
Lin Jiayi()
Dai Lun()
Xu Jiegui()
Journal Title:
CHINESE JOURNAL OF DIABETES
Issue:
Volume 8, Issue 05, 2000
DOI:
Key Word:

Abstract: Objective To investigate the effects of puerar in injection on the diabetic preipheral neuropathy (DPN).Methods Comparing sixty-six cases in puerar treat group with twenty-two cases in mecobalamin control group.And observing the effects of puerar in injection on the electromyo graphy,FBG,HbAlc,hemorheology and erythrocyte polyol.Results Marked effective rate:51.51% (treat group);22.72% (control group) ( P <0 01).Effective rate:89.39% (treat group ); 58.10% (control group) ( P <0 05).In treat group after treatment,FBG fell slightly without any meaning in statistics ( P >0 05);HbA1c decreased markedly ( P <0 01);hemorheology improved evidently;erythrocyte polyol decreased conspicuously ( P <0 01).Conclusion Puerar in injection has a good effect in DPN remedy.

  • [1]钱肇仁,钟学礼.糖尿病神经病变.上海医学,1984,7:426.
  • [2]潘长玉.糖尿病神经病变.方圻主编.现代内科学.北京:人民军医出版社.1996:2733.
  • [3]周运鹏.葛根的药理作用和临床应用研究进展.中西医结合杂志,1984,4:699.
  • [4]李淑梅,刘斌,陈海芬,等.葛根素注射液对急性心肌梗塞患者血浆内皮素及血管紧张素系统的影响.中国中西医结合杂志,1997,17:340.
  • [5]Brownlee M.Glycafion and diabetic complications.Diabetes,1994,43:836.
  • [6]段有金,王韶颖,三轮一智,等.五种中药对蛋白质非酶糖基化的抑制作用.中国糖尿病杂志,1998,6:229.
  • [7]Kador PF,Kinoshita JH.Role of aldose reductase in the development of diabetes-associated complications.Am J Med,1985,79:8.
  • [8]Masson EA,Boulton AJM.Aldose reductase inhibitors in the treatment of diabetic neuropathy.Druge,1990,39:190.
  • [9]张家庆,周云平.部分中药或其成分对大鼠晶体醛糖还原酶的抑制作用.中国中药杂志,1989,14:45.
WanfangData CO.,Ltd All Rights Reserved
About WanfangData | Contact US
Healthcare Department, Fuxing Road NO.15, Haidian District Beijing, 100038 P.R.China
Tel:+86-010-58882616 Fax:+86-010-58882615 Email:yiyao@wanfangdata.com.cn