Abstract： Objective To search the main points of clinical therapy and nursing for infective raw surface by suction wound closure therapy. Methods 1To treat infective raw surface by vacuum sealing drainage dressing. Observe the clinical therapy and nursing efficacy. Results From November 2008 to October 2010,thirty patients of infective raw surface were treated by this method. The good function and certain result were achieved. The clinical therapy and nursing results were satisfactory with no complications. Conclusion Treatment of infective raw surface by suction wound closure therapy is an ideal and effective method for the management of infective raw surface. Intimate nursing observation and drainage tube administration are the key points of nursing.