Observation of treatment and nursing care for pemetrexed treatment of advanced non-small cell lung cancer

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Author:
ZHENG Yu-xiu(Oncological Department, Jining Medical College Affiliated Rizhao People Hospital, Rizhao Cancer Therapy Center. Rizhao 276826, China)
ZHAO Feng-xiao()
MENG Ling-xin(Oncological Department, Jining Medical College Affiliated Rizhao People Hospital, Rizhao Cancer Therapy Center. Rizhao 276826, China)
Journal Title:
CHINA CLINICAL PRACTICAL MEDICINE
Issue:
Volume 04, Issue 12, 2010
DOI:
10.3760/cma.j.issn 1673-8799.2010.12.154
Key Word:
Pemetrexed;Advanced non-small cell lung cancer;Toxicity;Care

Abstract: Objective To observe the pemetrexed treatment of advanced non-small cell lung cancer and toxicity, corresponding to explore nursing. Methods 32 cases of elderly patients with advanced non-small cell lung cancer patients were infused pemetrexed in order to evaluate efficacy, toxicity, and implement appropriate care measures. Results 32 patients with advanced non-small cell lung cancer patients with pemetrexed treatment, complete remission (CR) 2 patients and partial remission (PR) 17 cases, stable (SD) 6 cases and progress (PD)7 cases. Toxicity occurs mainly in bone marrow suppression, gastrointestinal reactions, allergic reactions and drug extravasation and so on. 2 cases Ⅱ myelosuppression, 1 Ⅳ myelosuppression; Ⅱ nausea and vomiting in 19 cases, 5 cases of mild constipation; 2 patients had severe skin itching. The effective symptomatic treatment and active care measures have been eased. Conclusion Pemetrexed treatment of advanced non-small cell lung cancer patients, master the correct method of administration, toxicity of timely symptomatic treatment and care interventions can improve the quality of life of patients.

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