Abstract: Objective The goal observation unites with the compound prescription salvia mihiorrhiza drop pill is treating diabetes nephrosls (DN)3 issue of curative effects. Methods The method chooses 156 example diabetes nephrosis 3 issue of patients, in the convention uses ACEI kind or in the ARB kind of pharmacological treatment foundation, 80 examples add with the compound prescription salvia mihiorrhiza drop pill treat.12 weeks later compares around the treatment the clinical target change. Results The result union use compound prescription salvia mihiorrhiza drop pill treats diabetes nephrosis effectiveness 95%, urinates the protein quantity obvious reduction. Conclusion The conclusion compound prescription salvia miltiorrhiza drop pill may use in treating diabetes nephrosis jointly, may reduce the urine protein quantity obviously, delays diabetes nephrosis the progress,improves the patient quality of life.