Control of release preparation and quality in ephedrine hydrochloride and nitrofurazone nasal drops

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Author:
ZHANG Li-na(Weihai Municipal Hospital, Shandong 264200, China)
LIU Bing-bo(Weihai Municipal Hospital, Shandong 264200, China)
YU Yong(Weihai Municipal Hospital, Shandong 264200, China)
()
Journal Title:
CHINA CLINICAL PRACTICAL MEDICINE
Issue:
Volume 04, Issue 12, 2010
DOI:
10.3760/cma.j.issn 1673-8799.2010.12.31
Key Word:
Sodium hyaluronate;Nose drops;Preparation;Quality control

Abstract: Objective To develop ephedrine hydrochloride and nitrofurazone release nasal drops and to investigate the effects of relieving nasal congestion in acnte and chronic rhinitis. Methods To draw up the preparation technology of ephedrine hydrochloride and nitrofurazone release nasal drops, studying the stability of the preparation. Results The preparation was no difference with the control group by stability experiment. Af-ter room temperature, the character, color, content and pH was no significant change. Conclusion Ephedrine hydrochloride and nitrofurazone release nasal drops has a long residence tine in the nasal cavity, good efficacy and safety.

  • [1]中华人民共和国卫生部药政局.中国医院制剂规范,西药制剂.中国医药科技出版社,1999:165.
  • [2]郭温迎,陈爱兰.呋麻滴鼻液的制备及临床应用.海峡药学,2004,16(1):35-37.
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