Abstract： Objective To investigate the cardiovascular and cerebrovascular diseases, check serum homocysteine compared with the lipids examined. Methods with the hospital over the same period 200 cases of healthy persons(control group)to observe the control group and study group before treatment and after 15 of serum homocysteine and serum lipids were compared. Results In control group and study group before treatment Hcy comparison(P ＜0. 01)significant difference. Control group and study group after treatment compared Hcy (P ＞ 0.05) no significant difference. Blood lipid control group and study group were compared (P ＞ 0.05) no significant difference. Conclusion In this group of patients with cardiovascular disease examination and serum homocysteine blood examination, observation early in the disease was significantly higher Hcy, Hcy after treatment basically reduced to normal levels, while the study group and control group blood lipid no significant difference, compared to no significant difference. Fully illustrated examination of serum homocysteine in patients with cardiovascular and cerebrovascular diseases are the extent of disease and healing guidance, Hcy higher the more severe the illness, a higher probability of complications, in short, check the heart of serum homocysteine and cerebrovascular detected in patients has important significance, is worthy of extensive development and application.