Irbesartan in type 2 diabetic nephropathy treatment of microalbuminuria

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Author:
WANG Ming-guan(Department of Endocrinology, First People's Hospital of Shangqiu , Henan 467100, China)
Journal Title:
CHINA CLINICAL PRACTICAL MEDICINE
Issue:
Volume 04, Issue 12, 2010
DOI:
10.3760/cma.j.issn 1673-8799.2010.12.14
Key Word:
Type 2 diabetic nephropathy;Microalbuminuria;Irbesartan

Abstract: Objective To observe irbesartan combined conventional therapy in treating type 2 diabetic patients with microalbuminuria results. Methods 80 cases in hospital with type 2 diabetic patients with microalbuminuria were randomly divided into two groups, in the conventional hypoglycemic, anticoagulant, lipidlowering, low-protein diet on the basis of the treatment, the treatment group:plus Heuberger losartan; control group: conventional treatment without irbesartan. All patients before treatment and at 3 months of treatment, at 6months for blood glucose determination of flight(FBG), postprandial blood glucose(PBG), endogenous creatinine clearance rate(Ccr), blood urea nitrogen(BUN), 24 h Upro, UAER, ACR test, then the two groups before and after treatment were analyzed. Results The treatment group of type 2 diabetic nephropathy in patients with microalbuminuria, in the conventional hypoglycemic, anticoagulant, lipid-lowering, low-protein diet based treatment, on the plus irbesartan, treatment for 3 nonths, 6 months after the 24 h Upro, UAER, ACR significantly better than the control group. Conclusion Irbesartan treatment of type 2 diabetic microalbuminuria in clinical efficacy and reliable.

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