The clinical significance of serum tumor markers in the diagnosis of brest cancer

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Author:
XU Feng-liang(Rizhao hospital of Shandong province, Rizhao 2 76800, China)
WU Peng(Rizhao hospital of Shandong province, Rizhao 2 76800, China)
LI Yi-lei(Rizhao hospital of Shandong province, Rizhao 2 76800, China)
Journal Title:
CHINA CLINICAL PRACTICAL MEDICINE
Issue:
Volume 04, Issue 08, 2010
DOI:
10.3760/cma.j.issn 1673-8799.2010.08.44
Key Word:
Breast cancer;Serum;Tumor marker;Combined detection;Diagnosis

Abstract: Objective To explore the clinical significance of combined detection of serum CA153,TPS,CA125 in the diagnosis of breast cancer. Methods Technique of electrochem ilum inescence immunoassay was used to mesure serum CA153,TPS and CA125 levels. Results The levels and the positive rates of three kinds of markers in breast cancer patients were significantly higher than those of mammary benign patients and normal controls (P < 0. 01) , The diagnostic sensitivity and accuracy of combined detection were higher than that of single assay. Conclusion The combined detection of serum CA153,TPS, CA125 levels has important clinical significance in the diagnosis of breast cancer.

  • [1]陈智周,范振符,杨剑,等.肿瘤标志物CA153的免疫放射分析及其临床应用.中华肿瘤杂志,1998,20(20):125.
  • [2]Degoute CS,Ray M J,Gueugniauel P T,et al.Remifentanil Induces Consistent Controlled Hypotension in Children during Middle Ear Surgery.Can J Anaesth,2003,50:270 -276.
  • [3]范振符,陈智周.肿瘤标志物的研究与临床应用评价.标记免疫分析与临床,2002,9(2):441-443.
  • [4]Massidda B,Lonta MT,Forddi MR,et al.Usefulness of pyridinium crosslinks and CA153 as markeers in metastatic bone breast carcinoma.Anticancer Res,1996,16 (4):2221-2225.
  • [5]Cion M.The Tumor Associated Antigen CA153 in Primary Breast Evaluation of 667 cases.Br J Cancer,1991,63:809.
  • [6]周新,涂植光.临床生物化学和生物化学检验.人民卫生出版社,2003,448-470.
  • [7]叶伟民,韩焕,孔宪涛.肿瘤标志物CA125测定及其临床意义.中国免疫学杂志,1999,15(11):522.
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