Abstract: Objective To observe the therapeutic effects on ultrasound guidance for treatment of renal cysts.Methods Renal cysts in 69 cases were treated.Anhydrous ethanol was injected into the cysts for sclerosis under the ultrasound guidance for percutaneous puncture procedures.Results All the 59 cases were punctured successfully and followed up 1 month to 2 years.The effectictive rate was 100%.The curative rate was 92%.Conclusion This method is easy to practice with less complications and good effects.Therefore,it can be chosen as the first selection for renal cyst diagnosis and treatment.