Abstract: Objective To compare the effect of different intensity of upper and lower extremity exercise with elderly COPD patients of pulmonary rehabilitation. Methods 73 stable elderly COPD patients were divided into two groups randomly. After a baseline multi-dimensional assessment, patients underwent a 12-week rehabilitation cycle including training higher and lower exercise intensity of the upper and lower extremities, The pulmonary function ,6-minute walking distance, baseline dyspnea index, BMI and ellipsis were evaluated and compared between pre and post-training. Results After 12-weeks of different intensity of the upper and lower extremities,compared with lower exercise intensity group, higher exercise intensity group were improved significantly on 6minute walking distance and dyspneic symptom( P < 0.01 ), but lost were high (P < 0.05 ). The pulmonary function, BMI were not increased between pre and post-training. Conclusion The two different intensity of the upper and lower extremities were proved to be effective for improving the dyspneic symptoms and exercise tolerance with stable elderly COPD patients. Compared with lower exercise intensity group, higher exercise intensity group were improved significantly, but lost were high. The pulmonary function, BMI were not increased between pre and post-training.