Abstract: Objective To semiquantitaively evaluate the stiffness of breast solid lesions with ultrasonic elastogaphy.Methods.Strain images of 228 solid lesions from 118 patients were got with ultrasonic elastography.Comparing the strain ratio of lesion to different breast tissue,then getting the stiffness ratio of lesion to breast tissue.Results 176 were breast glandular tissue in the same level with the lesions:11 were fat:41 were both glandular tissue and fat.10 had no glandular tissue as the reference in the strain images;10 had no flat as the reference.The stiffness of the lesions were different with different level glandular tissue as reference.The stiffness of the lesions were different with the same level breast tissue as referenee and superior-level fat tissue as reference.Conclusion Using the strain ratio measure method with the same level breast tissue as the reference.,the stiffness of a breast solid lesion could be objectively evaluated.