A Case of amyopathic dermatomyositis with Hashimoto's thyroiditis and breast cancer

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Author:
HUANG Hui(Department of Neurology,Huaibei People's Hospital,Huaibei 235000,Anhui,China)
LIU Yan(Department of Neurology,Huaibei People's Hospital,Huaibei 235000,Anhui,China)
ZHAO Yu-hong(Department of Neurology,Huaibei People's Hospital,Huaibei 235000,Anhui,China)
Journal Title:
CHINA CLINICAL PRACTICAL MEDICINE
Issue:
Volume 2, Issue 07, 2008
DOI:
Key Word:
Amyopathic dermatomyesitis;Hashimoto's thyroiditis;Breast Cancer:Muscle histochemistry

Abstract´╝Ü Objective To investigate the clinical manifestation of amyopathic dermatomyositis with other auto-immunological diseases and malignancy.Methods A case of amyopathic dermatomyositis with Hashimoto's thyroiditis and breast cancer has reported.Electromyography and pathological examination of skin and muscle had been pedorrned.The patient was followed up in ten months.Results A skin lesions manifested by typical edematous rash of dermatomyositis without muscle weakness had been found.The pathology of skin and muscle showed inflammation cells rounded skin and intramuscular capilaries without muscle degeneration.There were no changes in the muscular enzymes and the electromyography.It was found a Hashimoto's thyroiditis 2 months and a breast cancer 8 months after the onset.The skin lesions were attenuated by anti-thyroiditis and anti-cancer,respectively.Conclusion Amyopathic dermatomyositis may be associated with other anto-immunological diseases and cancer.

  • [1]Cosnes A,Amaudric F,Gherarth R,et al.Dermatomyositis without muscle weakness.Long-term follow-up of 12 patients without systemic corticosteroids.Arch Dermatol,1995,131:1381-1385.
  • [2]Gerami P,Schopa JM,McDonald L,et al.A systematic review of adult-onset clinically amyopathic derrnatomyositis(dermatomyositis sin6myositis):a missing link within the spectrum of the idiopathic inflammatory myopathies.J Am Acad Dermatol,2006,54:597-613.
  • [3]El-Azhary RA,Pakzad SY.Amyopathic dennatomyositis:retrospective review of 37 cases.J Am Acad Dermatol,2002,46:560-465.
  • [4]Finger DR,Dunn CL,Gilliland WR,et al.Amyopathie derrnatomyositis associated with malignancy.Int J Dermatol,1996,35:663-664.
  • [5]Fung WK,Chan HL,Lain WM.Amyopathic dermatomyositis in Hong Kong-association with nasopharyngeal carcinoma.Int J Dermatol,1998,37:659-663.
  • [6]Maddison P.Cancer types in dermatomyositis and polymyositis.Lancet,2001,357:1443.
  • [7]Stockton D,Doherty VR,Brewster DH.Risk of cancer in patients with dennatomyositis or polymyositis and follow-up implications:a Scottish population-based cohort study.Br J Cancer,2001,85:41-45.
  • [8]Celebi S,Gol A,Kamali S,el al.Amyopathie dermatomyositis associated with cervical cancer.Clin Rhematol,2001,20(6):438-440.
  • [9]Goyal S,Nousari HC.Paraneoplastie amyopathic dermatorayositis associated with breast cancer recurrenec.J Am Acad Dermatol.1999,41(5 Pt 2):874-875.
  • [10]Saoud B,Allali F,Hassouni NH.Amyopothic dermatomyositis.Joint Bone Spine,2006,73:318-320.
  • [11]Callen JP.When and how should the patient with dennatomyositis or amyopathic dermatomyositis be assessed for possible carncer Arch Dermatol,2002,138:969-971.
  • [12]Osako T,Ito Y,Morimatsu A,et al.Flare-up of dermatomyositis along with recurrence of breast cancer.Breast J,2007,13:200-202.
  • [13]Kato H,Uyeki Y,Kitajima Y,et al.A case of dermatomyositis and Hashimoto's thyreiditis.J Dennatol,1988,15:273-275.
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