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Relationship between Chlamydla Pneumoniae Infection anti Serum Levels of Blood Fat in Elderly Patients with Infarction

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Author:
No author available
Journal Title:
CHINA CLINICAL PRACTICAL MEDICINE
Issue:
5
DOI:
No doi available
Key Word:
肺炎衣原体;脑梗死;C反应蛋白;高脂血症;Chlamydia pneumoniae;Acute cerebral infarction;C-reactive protein;Hperlipidemia

Abstract: Objective To investigate the relationship between Chlamydia pneumoniae (Cpn)infection in infartion of elderly patients. Methods The serums peeific antibodies to CpnIgG were measured by using microimmunofluoreseence technique in 80 healthy subjects as control group and 88 elderly infarction patients. The levels of blood-fat were examined. Results The positive rate of Cpn specific IgG antibody was 79.5% in infarction group,47.8% in control group, the patients with infarction had significantly higher positive rate of CpnIgG than the subjects in control group(P<0.01). Total cholesterol, triglycerides(TG) ,low density lipoprotein cholesterol(LDL-C), apolipoproteinA (apoA), pdipoproteinB (apoB) in infarction group were higher than those in control group(P<0.01) ,while high density lipoprotein cholesterol(HDL-C)in infarction group was significantly lower than that in control group(P<0.01). Cpn IgG is related positively to TG,LDL-C and apoA(r=0.47, 0.65,0.43) ,but negatively to HDL-C in infarction group (r=-0.81)(P<0.01). Conclusion Cpn infection is also an important risk factor for ischemic stroke, particularly in elderly patients, Cpn infection may play a role in the pathogenesis of infarction through lipid metabolic disturbance.

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