The Expression Of Nuclear Factor-κB And Cyclooxygenase 2 In Large Bowel Carcinoma And Their Relation To Angiogenesis

( views:, downloads: )
Author:
ZHU Huiming()
WANG Lisheng()
HUANG Xun()
()
()
()
()
Journal Title:
CHINA CLINICAL PRACTICAL MEDICINE
Issue:
Volume 1, Issue 01, 2007
DOI:
Key Word:

Abstract:

  • [1]Hinz M,Krappmann D,Eichten A,et al.NF-κB function in growth control:regulation of cychn D1 expression and G0/G1 to S-phase transition[J].Mol Cell Bio1,1999,19(18):2690-2698.
  • [2]Wang C Y,Mayo M W,Kimeluk R G,et al.NF-κB antiapoptosis:induction of TRAF1 and TRAF2 and c-IAPI and c-IAP2 to suppress caspase-8 activation[J].Science,1998,281 (10):1680-1683.
  • [3]Soslow R A,Dannenberg A J,Rush D,et al.Cox-2 is expressed in human puhnonary,colonic and mammary tumors[J].Cancer,2000,89(12):2637-2645.
  • [4]Wang Y,Dang J,Wang H,et al.Identification of a novel nuclear factor-kappa B sequence involved in expression of urokinase-type plasminogen activator receptor[J].Eur J Biochem,2000,267(11):3248-3254.
  • [5]Sovak M A,Bellas R E,Kim D W,et al.Aberrant NF-κB/Rel expression and the pathogenesis of breast cancer[J].J Clin Investig,1997,100(12):2952-2956.
  • [6]王维,罗和生,余保平,等.人胃癌及癌前病变中NF-KappaB和c-myc蛋白的表达与意义[J].肿瘤防治研究,2002,29(4):285,287.
  • [7]Lim G,Boyle J O,Morgan D,et al.Cyclooxygenase-2 expression is up-regulated in gastric carcinoma[J].Cancer Res,1999,59 (7):991-994.
  • [8]Uefuji K,Ichikura T,Mochizuki H.Cyclooxygenase-2 expression is related to prostagladin biosynthesis and angiogenesis in human gastric cancer[J].Clin Cancer Res,2000,6 (1):135-138.
  • [9]Kondo M,Yamamoto H,Nagano H,et al.Increased expression of Cox-2 in nontumor liver tissue is associated with shorter disease-free survival in patients with hepatocellular carcinoma[J].Clin Cancer Res,1999,5 (12):4004-4012.
  • [10]Tsujii M,Kawano S,Tsuji S,et al.Cyclooxygenase regulates angiogenesis induced by colon cancer cells[J].Cell,1998,93 (5):705-716.
  • [11]Liu X H,Kirschenbaum A,Yao S,et al.Inhibition of cyclooxygenaae-2 suppresses angiogenesis and the growth of prostate cancer in vivo[J].J Urol,2000,164(4):820-825.
  • [12]Hsu A L,Ching T T,Wang D S,et al.The cyclooxygenase-2 inhibitor celecoxib induces apoptosis by blocking Akt activation in human prostate cancer cells dependently of bcl-2[J].J Biol Chem,2000,275 (57):11397-11405.
  • [13]Masferrer J L,Leahy K M,Koki A T,et al.Antiangiogenic and Antitumor activities of cyclooxygenase-2 inhibitors[J].Cancer Res,2000,60(7):1306-1342.
WanfangData CO.,Ltd All Rights Reserved
About WanfangData | Contact US
Healthcare Department, Fuxing Road NO.15, Haidian District Beijing, 100038 P.R.China
Tel:+86-010-58882616 Fax:+86-010-58882615 Email:yiyao@wanfangdata.com.cn