Study on the detection of serum β2-MG, RBP and Cys-C test for early diagnosis of acute kidney injury

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ZHONG Fang-cai(Department of Clinical Laboratory, the First People's Hospital of Neijiang, Neijiang, Sichuan 641000, China)
Journal Title:
Chinese Journal of Primary Medicine and Pharmacy
Volume 19, Issue 20, 2012
Key Word:
β2-microglobulin ; Retinal binding protein ; Cystatin C; Acute kidney injury(AKI)

Abstract: Objective Through different disease period the serum β2-microglobulin (β2-MG),Retinal binding protein (RBP) and Cystatin C (Cys-C) joint test,to evaluate the clinical value of the combination detection of early diagnosis of acute kidney injury (AKI).Methods Our choice in March 2011 to February 2012 in the same period and 88 patients with AKI physical examination in 63 cases,in the new HITACHI7600-020 automatic biochemistry analyzer and into test sample β2-MG,RBP and Cys-C content.Results The patients with AKI of serum β2-MG,RBP and Cys-C compared with the control were significantly increased,the differences were significant ( P < 0.05 or P <0.01 ).Conclusion Serum β2-MG,RBP and Cys-C are sensitive idicators in early diagnosis of AKI,three united detection help early diagnosis AKI,clinical doctors can provide reliable accurate valuable diagnostic basis for guidance.

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