Abstract： Objective To compare the safety and efficacy of ligature between traditional ligation way in gastrectomy.Methods 60 patients with gastrointestinal cancioma were selected and randomly divided into two groups,30cases of ligature(treatment group),30 cases of ligation (traditional group).Results The operative time,blood loss,postoperative hospital stay,complications and treatment costs was compared between the two groups.Compared with the traditional group,there were shorter treatment time,reduced bleeding,shorter hospital stay,fewer complications,reduced treatment costs in treatment group.Conclusion Ligature gastrectomy is safe and effective.