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Evaluation of screening programs for cervical cancer

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Author:
No author available
Journal Title:
Chinese Journal of Primary Medicine and Pharmacy
Issue:
17
DOI:
10.3760/cma.j.issn.1008-6706.2012.17.002
Key Word:
宫颈肿瘤;醋酸染色;Cervical tumor;Acetic acid

Abstract: Objective To evaluate the values of visual inspection with acetic acid( VIA) and human papillomavirus( HPV) and thinprep cytology test( TCT) in the screening of cervical cancer.Methods VIA,HPV test and TCT in 946 women was conducted.Cervical biopsy or endocenical curettage( ECC) was performed in VIA positive women or HPV positive women or TCT positive women. The pathologic outcome was as the gold standard,and the out come more and equal to cervical intraepithelial neoplasia( CIN) Ⅱ were identified as positive.Results There was no significant difference among three groups in sensitivity rate( 73.l%,96.2,88.5% ) and negative predictive value ( 99. 1% ,99.9% ,99.7% ) ( all P > 0.05 ).The specificity rate (97.5% ) and positive predictive value ( 50.O% ) of TCT was better than those of HPV ( 93.5%,29.4% ),and HPV was better than those of VIA( 87.0%,13.7% ),and the difference had statistifical significance among three groups ( x2 =71.34,26.00,22.17,8.28,all P < 0.05 ).Conclusion Although the rate of missed diagnosis and misdiagnosis rate was higher than that of HPV and TCT,but VIA seems to be appropriate methods in the screening of cervical cancer owing to its low price.

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