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The clinical significance of dynamic changes of serum D-dimers in esophageal carcinoma pre-and post-operation

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Author:
No author available
Journal Title:
Chinese Journal of Primary Medicine and Pharmacy
Issue:
13
DOI:
10.3760/cma.j.issn.1008-6706.2012.13.005
Key Word:
食管肿瘤;D-二聚体;生存率;Esophageal neoplasms;D-dimer;Survival rate

Abstract: Objective To investigate the relationship between dynamic changes of plasma D-dimer and survival rate of the esophageal carcinoma patients pre-and post-operation.Methods 30 cases of normal control group,160 cases of esophageal cancer group( including operation cases n =112),with the gold standard method for the determination of plasma D-dimer.Results There was a link between the level of D-dimer,TNM staging,lymph node metastasis and tumor size in esophageal carcinoma patients.Compared with the preoperation,the plasma D-dimer is significantly elevated 2 years later( t =7.35,P > 0.05 ).Conclusion Before or after the operation,dynamic changes of plasma D-dimer had a relationship with short-term survival rate.

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