Application of nasal continuous positive airway pressure in the treatment of neonatal respiratory disease

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WANG Hui-qin(Department of Newborn Pediatric, the Maternal and Child Health Hospital of Hefei,Hefei ,Anhui 230001, China)
GUO Ben-biao(Department of Newborn Pediatric, the Maternal and Child Health Hospital of Hefei,Hefei ,Anhui 230001, China)
Journal Title:
Chinese Journal of Primary Medicine and Pharmacy
Volume 19, Issue 10, 2012
Key Word:
Nasal continuous positive airway pressure;Respiratory disease;Newborn

Abstract: Objective To observe the effects of nasal continuous positive airway pressure(NCPAP) on neonatal respiratory disease.Methods 67 newborns with respiratory disease undergone the treatment of NCPAP and routine clinic treatment.The changes of blood gas index and therapeutic effects were observed.The changes of blood gas between the pretherapy and post-treatment were compared.Results The numerus of PaO2,SpO2 was increased apparently at 1 hour after treament with NCPAP.The difference was significant ( t =3.84,15.50,all P < 0.05 ).But the PaCO2 had no apparent change and the difference was not significant(t =1.96,P > 0.05 ).54 newborns were treated successfully and 13 newborns were treated unsuccessfully.51 newborns were cured,11 newborns were improved and 1 patient was dead at Last.Conclusion The early application of NCPAP on neonatal respiratory disease was very effective.It could reduce the use of mechanial ventilation,and it was a convenient,safe and effect-prominent method.

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