Abstract： Objective To explore the dinical significance of C-reactive protein(CRP) testing for diagnosis and treatment of children with bronchial pneumonia.Methods 341 samples of children with acute respiratory infections were detected with CRP quantitative analysis and CRP level and CRP positive rates were compared with 150 heahhy children as control specimens.Results According to diagnostic criteria,128 cases of bacterial pneumonia were found in 341 patients,accounting for 37.54％,CRP positive rate was 95.31％ ; 151 cases of mycoplasma pneumonia,accounting for 44.28％,CRP positive rate was 31.13 ％ ; and 62 cases of viral pneumonia,accounting for 18.18％,CRP positive rate was 6.45 ％.CRP levels,CRP-positive rates of bacterial pneumonia,mycoplasma pneumonia,viral pneumonia compared with the control group were significantly different ( P ＜ 0.01 ).Conclusion CRP of mycoplasma pneumonia increased significantly than viral pneumonia,thus CRP could be used as an important secondary pathogen detection indicators for identification and diagnosis of mycoplasma pneumonia.