Diagnostic and predictive value of troponin I hy persensitive C-reactive protein and lactic acid in viral myocarditis
- Author:
- No author available
- Journal Title:
- Chinese Journal of Primary Medicine and Pharmacy
- Issue:
- 1
- DOI:
- 10.3760/cma.j.issn.1008-6706.2012.01.003
- Key Word:
- C-反应蛋白质;心肌肌钙蛋白Ⅰ;血乳酸;病毒性心肌炎;Troponin I;Lactic acid,hypersensitive C-reactive protein;Viral myocarditis
Abstract： Objective To explore the diagnostic and predictive value of troponin Ⅰ,lactic acid and hypersensitive C-reactive protein(hs-CRP) in viral myocarditis.Methods Troponin Ⅰ,hs-CRP,lactic acid blood levels in different time were measured in 88 patients with acute viral myocarditis(54 cases) or acute upper respiratory infections (34 cases).Troponin Ⅰ leyel in patients with severe 39 cases and mild VMC 15 cases were compared.Results Troponin Ⅰ level of VMC group was (0.59 ±0.10) ng/L,and significantly higher than that of acute upper respiratory infection group [ (0.10 ± 0.08 ) ng/L ] ( t =2.79,P ＜ 0.05 ).And higher lactic acid and hs-CRP level were observed at different period ( t =2.71,2.48,all P ＜ 0.05).Conclusion Troponin I could help diagnose VMC predict the severity of myocarditis to some extent.Lactic acid and hs-CRP could also reflect imflammation injury of VMC.
- [1]童美琴.病毒性心肌炎患者血清心肌肌钙蛋白Ⅰ检测的临床意义[J].2011,(4).
- [2]陈幼芳,杜心清,许朝祥,等.超敏C-反应蛋白、肌钙蛋白I与急性冠状动脉综合征患者近期心脏事件的相关性[J].2007,(3).
- [3]吴凡,谢家斌,邱汉婴.细胞因子治疗病毒性心肌炎的研究进展[J].2004,(2).
- [4]Y J, Kang.Molecular and cellular mechanisms of cardiotoxicity.[J].2001,109 Suppl 1.
- [5]Babuin L,Jaffe AS,Apple FS.Biomarkers in acute cardiac disease: the present and the future.[J].2006,48(1).
- [6]Kim, Greaves,John S, Oxford,Christopher P, Price,etc.The prevalence of myocarditis and skeletal muscle injury during acute viral infection in adults: measurement of cardiac troponins I and T in 152 patients with acute influenza infection.[J].2003,163(2).
- [7]Freixa X,Sionis A,Castel A.Low troponin-I levels on admission are associated with worse prognosis in patients with fulminant myocarditis.[J].2009,41(6).
- [8]Ethan G, Leonard.Viral myocarditis.[J].2004,23(7).