Abstract: Objective To investigate the effects of uterine malformation on the pregnancy and delivery, and to accumulate experience of uterine malformations obstetric clinical diagnosis and treatment of perinatal. Methods The clinical data of 4 273 cases of pregnant women were retrospectively analyzed. Of them,45 patients with uterine malformation. The effects of uterine malformation on the pregnancy and delivery were evaluated. Results The ratio of development of premature delivery, premature rupture of membranes, abnormal fetal position, retained placenta and perinatal complications in uterine malformation pregnancy group was significantly higher than normal uterine pregnancy group(P<0.05).The ratio of cesarean section in uterine malformation group also significantly higher than the yield of normal uterine pregnancy(82.2%vsl6.93% ,P<0.05). Conclusion Pregnant women with uterine malformations had more obstetric complications, higher operative delivery rate, the uterine malformation was high risk factor for the pregnancy,clinical attention should be paid.