Abstract: Objective To explore clinical characteristics and prevention measure in the patients with hepatic cirrhosis complicated MOF.Methods To analyse summarily the clinical manifestation,induction factor,incidence morbidity and the treatment tendency of 30 patients with hepatic cirrhosis complicated MOF.Results Among 30 patients,25 cases complicated by concurrent central nervous system failure,21 cases complicated with gastrointestinal tract bleeding;Total mortality was 43.3%,and 9 cases concurrent four-organ failure,all died.Conclusion Hepatic cirrhosis complicated MOF commonly involved organs are brain,gastrointestinal trad,kidney,blood system,heart and lung.The more the failed organs are,the higher the case mortality rate is.Prompt and effective treatment of induction factor for patients suffering from hepatic cirrhosis can lower MOF rate and prolong their survival period.