Abstract： Objective To observe the effect of Shenqichongcao capsule on oxidant/antioxidant imbalance in patients with chronic obstructive pulmonary disease (COPD).Methods Selected 30 COPD patients from treatment group and control group respectively.Pre- and post treatment,the changes of points of Syndromes and their SOD,LPO and NO of patients were observed and compared with normal group.Results The level of SOD and LPO of COPD patients were lower than normal group with shenqichongcao capsule.There was significant difference before and after treatment (P＜0.01).The control group had no significant difference.Conclusion The effect of Shenqichongcao capsule on the free radical injury in patients with COPD had some improving effect.