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The curative effect of cardiac resynchronization therapy in patients with refractory heart failure
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- Author:
- No author available
- Journal Title:
- CHINESE JOURNAL OF PRIMARY MEDICINE AND PHARMACY
- Issue:
- 5
- DOI:
- 10.3760/cma.j.issn.1008-6706.2007.05.002
- Key Word:
- 心脏起搏,人工;心力衰竭,充血性
Abstract： 目的 探讨心脏同步化治疗(CRT)对于难治性慢性心力衰竭的效果.方法 30例顽固性心力衰竭患者,NYHA分级为Ⅲ～Ⅳ级.采用心电图观察QRS时限、超声心动图计算LVEF,组织多普勒超声彩色心动图了解心室壁同步的情况;6 min步行距离测量心脏的负荷能力的变化.结果 (1)双心室起搏[(167±24)ms]和起搏前[(182±39)ms]、右心室起搏[(220±31)ms]、左心室起搏[(210±38)ms]比较QRS时限明显缩短(P＜0.05).(2)心功能分级(NYHA):术前Ⅲ～Ⅳ级,术后1周Ⅰ～Ⅱ级,术后1个月直至随访时仍旧Ⅰ～Ⅱ级.(3)LVEF:术后1周[(38.80±3.88)%]和术前[(27.30±28.94)%]比较明显提高(P＜0.05),随访时[(39.65±6.75)%]和术前比较明显提高(P＜0.05).(4)6 min步行距离:术后1周[(479±123)m]和术前[(388±165)m]比较有明显提高(P＜0.05).结论 CRT短期可以减轻难治性心力衰竭患者的症状,增加其运动能力,改善心脏功能.
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