You Position: Home > Paper
Ultrasonic changes and clinical observation of enalapril and indapamide to reverse left ventricular hypertrophy in essential hypertension
( views:60, downloads:8 )
- Author:
- No author available
- Journal Title:
- CHINESE JOURNAL OF PRIMARY MEDICINE AND PHARMACY
- Issue:
- 3
- DOI:
- 10.3760/cma.j.issn.1008-6706.2007.03.006
- Key Word:
- 依那普利;吲达帕胺;高血压;肥大,左心室;超声心动描记术
Abstract： 目的 观察依那普利和吲达帕胺对原发性高血压伴左心室肥厚(LVH)的逆转作用.方法 将136例原发性高血压患者随机分为治疗组(n=68)和对照组(n=68),治疗组给予依那普利和吲达帕胺;对照组给予吲达帕胺.分别于服药前及服药6个月后测量血压,观察24 h动态血压、心电图、超声心动图改变.结果 两组治疗后收缩压及舒张压均较治疗前有明显降低(P＜0.01),心功能指标较治疗前明显改善(P＜0.05),高血压伴LVH有明显的逆转作用(P＜0.05～0.01).结论 依那普利和吲达帕胺均有逆转LVH作用,两者联合应用在逆转LVH方面优于单独使用吲达帕胺.
- [1]胡家庭,濮艳姑.依那普利和卡维地洛治疗充血性心力衰竭60例临床观察[J].2005,(4).
- [2]李鸣皋,马贵喜,孙运峰,等.血管紧张素-Ⅱ对急性缺氧时血管内皮细胞分泌内皮素的影响及金钠多的保护作用研究[J].2005,(19).
- [3]A, Ganau,R B, Devereux,M J, Roman,etc.Patterns of left ventricular hypertrophy and geometric remodeling in essential hypertension.[J].1992,19(7).
- [4]Alvarez BV,Camilion-de-Hurtado MC,Cingolani HE,etc.Enalapril induces regression of cardiac hypertrophy and normalization of pHi regulatory mechanisms.[J].1998,31(4).
- [5]D, Levy,R J, Garrison,D D, Savage,etc.Prognostic implications of echocardiographically determined left ventricular mass in the Framingham Heart Study.[J].1990,322(22).
- [6]Bjorn Dahlof,Richard B. Devereux,Stevo Julius,etc.Characteristics of 9194 Patients With Left Ventricular HypertrophyThe LIFE Study[J].1998,32(6).
- [7]Gueret P,Dubourg O,de-Cordoue A,etc.Centralized echocardiogram quality control in a multicenter study of regression of left ventricular hypertrophy in hypertension.[J].1998,16(4).
- [8]R B, Devereux,D R, Alonso,E M, Lutas,etc.Echocardiographic assessment of left ventricular hypertrophy: comparison to necropsy findings.[J].1986,57(6).