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Clinical significance of the Serum leptin levels in patients with post-hepatitis liver cirrhosis
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- Author:
- No author available
- Journal Title:
- CHINESE JOURNAL OF PRIMARY MEDICINE AND PHARMACY
- Issue:
- 2
- DOI:
- 10.3760/cma.j.issn.1008-6706.2007.02.002
- Key Word:
- 肝硬化;瘦素;肝性脑病
Abstract： 目的 测定肝炎后肝硬化患者血清瘦素水平,并探讨其异常变化的临床意义.方法 采用放射免疫法测定64例肝炎后肝硬化患者和40例对照者血清瘦素水平,同时测定肝功能、身高、体重,根据体重(kg)/身高2(m2)计算体重指数.分析肝硬化患者血清瘦索变化与肝功能、体重指数及肝性脑病的关系.结果 肝硬化患者的血清瘦素水平显著高于对照组,按Child-Pugh分级,血清瘦素水平逐渐升高.Child A级血清瘦素水平较对照组升高,但差异无统计学意义;Child B和 Child C级的血清瘦素水平均显著高于对照组.经相关分析发现瘦素水平与Child-Pugh分级有相关性,与体重指数、总蛋白、白蛋白水平无关.结论 肝炎后肝硬化患者的血清瘦素水平明显升高,与肝功能密切相关.
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