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Observation of chemotherapy with GP and NP on post-operative patients of non-small cell lung cancer
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- Author:
- No author available
- Journal Title:
- CHINESE JOURNAL OF PRIMARY MEDICINE AND PHARMACY
- Issue:
- 1
- DOI:
- 10.3760/cma.j.issn.1008-6706.2007.01.001
- Key Word:
- 癌,非小细胞肺;抗肿瘤联合化疗方案;吉西他滨;长春瑞滨
Abstract： 目的 观察非小细胞肺癌术后患者采用顺铂联用吉西他滨或长春瑞滨方案(GP或NP方案)化疗的近期疗效和不良反应.方法 选取85例非小细胞肺癌术后患者,随机分为GP化疗组和NP化疗组,观察两组患者在化疗期间的死亡率、转移、复发和化疗毒副反应发生情况.结果 化疗期间非化疗原因死亡3例,GP组2例,NP组1例.复发:GP组2例,NP组1例.转移:GP组6例,NP组7例.近期疗效两组无明显差异.两组化疗的主要毒性反应均为骨髓抑制和恶心、呕吐.GP组血小板减少高于NP组;NP组白细胞减少和血红蛋白下降高于GP组;两组恶心、呕吐的发生率相似.两者毒副作用均可耐受.结论 GP和NP方案均可作为非小细胞肺癌术后患者化疗的一线方案,前者毒副作用低于后者.
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