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Efficacy and safety of diclofenac sodium paste in the treatment of primary osteoarthritis of the knee
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- Author:
- No author available
- Journal Title:
- CHINESE JOURNAL OF PRIMARY MEDICINE AND PHARMACY
- Issue:
- 6
- DOI:
- 10.3760/cma.j.issn.1008-6706.2006.06.001
- Key Word:
- 骨关节炎;双氯芬酸钠;治疗结果
Abstract： 目的研究双氯芬酸钠贴片治疗骨性关节炎的有效性及安全性.方法采用随机、单盲、阳性药物平行对照方法,试验组给予双氯芬酸钠贴片,对照组给予双氯芬酸钠乳胶剂.记录治疗前后患者和医师对药物疗效的评价,监测不良事件的发生.结果试验组和对照组患者对疼痛评价和总体评价的评分治疗后较治疗前下降,医师对关节压痛指数和总体评价的评分治疗后较治疗前下降,治疗后患者疼痛症状减轻.治疗过程中未见皮肤有水肿、发红、皮疹、瘙痒等及全身不适反应.血常规、肝功能、肾功能各项指标治疗前后差异无统计学意义.结论双氯芬酸钠贴片是治疗骨性关节炎的安全有效、使用方便的外用镇痛抗炎药.
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