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The influence of irbesartan on QT correction dispersion of the hypertensi patient with LVH
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- Author:
- No author available
- Journal Title:
- CHINESE JOURNAL OF PRIMARY MEDICINE AND PHARMACY
- Issue:
- 7
- DOI:
- 10.3760/cma.j.issn.1008-6706.2004.07.004
- Key Word:
- 厄贝沙坦;高血压;QT离散度
Abstract： 目的观察厄贝沙坦对高血压患者左室肥厚(LVH)的逆转作用及对QT离散度(QTd)和校正QTd(QTcd)的影响.方法 68例高血压患者分为LHV组38例和非LHV组30例,口服厄贝沙坦150 mg/d治疗后6个月观察治疗前后左室重量指数(LVMI)、QTd和QTcd的改变.结果两组患者用药后收缩压(SBP)和舒张压(DBP)显著降低(P＜0.01),LHV组治疗后较治疗前室性心律失常(VA)明显改善,LVMI显著降低、QTd和QTcd显著缩短(P＜0.01).结论厄贝沙坦具有良好的降压效果,还可逆转心肌肥厚,降低QTd和QTcd,减少恶性心律失常的发生,从而改善高血压LVH患者的预后.
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