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Study on gastroscopy with propofol
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- Author:
- No author available
- Journal Title:
- CHINESE JOURNAL OF PRIMARY MEDICINE AND PHARMACY
- Issue:
- 7
- DOI:
- 10.3760/cma.j.issn.1008-6706.2004.07.001
- Key Word:
- 异丙酚;消化内镜;镇静麻醉
Abstract： 目的探讨异丙酚静脉麻醉在胃镜检查中的最低有效剂量.方法选择60例胃镜检查的患者随机分为三组,分别静脉注射异丙酚1 mg/kg(A组)、1.5 mg/kg(B组)、2 mg/kg(C组),注射速度均为20 mg/10 s,观察记录术中镇静效果,不良反应,用药前、中、后心率、血压、血氧饱和度变化.结果 B组及C组镇静效果明显优于A组,不良反应少于A组(P＜0.05);三组用药中与用药前比较血压、心率有一过性下降,C组下降最明显(P＜0.01),C组下降幅度明显大于A组、B组(P＜0.01和P＜0.05);A组、B组血氧饱和度变化不大(P＞0.05),而C组术中血氧饱和度下降明显,与术前比较差异有显著意义(P＜0.01).结论异丙酚静脉麻醉用于胃镜检查是有效的,剂量控制在1.5 mg/kg为最低有效剂量.
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