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Expreesion of vascular endothelial growth factor(VEGF) and transforming growth factor-β1(TGF-β1) in patients with recurrent nasal polyps
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- Author:
- No author available
- Journal Title:
- CHINESE JOURNAL OF PRIMARY MEDICINE AND PHARMACY
- Issue:
- 4
- DOI:
- 10.3760/cma.j.issn.1008-6706.2004.04.004
- Key Word:
- 内窥镜;鼻息肉;细胞因子;免疫组化
Abstract： 目的探讨血管内皮生长因子(vascular endothelial growth factor,VEGF)和转化生长因子-β1(transforming growth factor-β1,TGF-β1)的表达与鼻息肉复发关系.方法 60例内窥镜鼻窦术后鼻息肉复发病人,用SP免疫组化染色法比较VEGF和TGF-β1的表达.结果 VEGF和TGF-β1在鼻息肉组织的血管内皮细胞和腺体细胞的表达明显高于中鼻甲组织(P＜0.01);鼻息肉临床分型与VEGF和TGF-β1的表达无关.结论 VEGF和TGF-β1的表达可能与鼻息肉复发有关,术后定期合理的鼻窦内窥镜随访是预防和减少复发的重要手段.
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