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The clinical observation of therapeutic effect of puerarin injection and methylcobalamin on pathological damage of peripheral nervous system caused by diabetes mellitus
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- Author:
- No author available
- Journal Title:
- CHINESE JOURNAL OF PRIMARY MEDICINE AND PHARMACY
- Issue:
- 10
- DOI:
- 10.3760/cma.j.issn.1008-6706.2003.10.005
- Key Word:
- 葛根素;弥可保;糖尿病;周围神经病变
Abstract： 目的观察葛根素、弥可保联合治疗糖尿病周围神经病变的疗效.方法 90例(男49例,女41例)2型糖尿病周围神经病变,随机分为两组,治疗组48例应用葛根素0.3 g,加入生理盐水250 ml,或木糖醇500 ml中静滴,1次/d;弥可保500 μg,肌注,1次/d.对照组42例用维生素B1 100 mg,肌注,1次/d;维生素B12 500 μg,1次/d.两组均以15 d为1个疗程.结果治疗组总有效率89.6%,对照组为64.3%,两组比较差异有显著意义(P＜0.01).药物不良反应轻微.结论在严格控制血糖、血脂、血压的基础上,联合应用葛根素、弥可保治疗糖尿病周围神经病变有较好的疗效,能减少糖尿病的致残率.
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