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Change of lipoprotein(α) in dialysis patients and its relationship with cardiac and cerebral events
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- Author:
- No author available
- Journal Title:
- CHINESE JOURNAL OF PRIMARY MEDICINE AND PHARMACY
- Issue:
- 7
- DOI:
- 10.3760/cma.j.issn.1008-6706.2003.07.003
- Key Word:
- 血液透析;腹膜透析;脂蛋白(α)
Abstract： 目的研究血透(HD)与腹透(PD)病人脂蛋白(α)[Lp(α)]水平变化及意义.方法分析45例HD及50例PD病人临床及实验室资料,比较两种透析方法对Lp(α)及脂质水平影响的差别,分析Lp(α)与其他相关因素的关系.结果两组TG和ApoB均显著增高,HDL-C显著降低.两组Lp(α)水平均较对照组显著升高(P＜0.05),PD组较HD组更高(P＜0.01);两组病人Lp(α)水平与UCG、ECG异常及心脑血管事件发生、TC及LDL-C浓度正相关;而与ALb浓度负相关.结论透析病人脂质代谢紊乱常见,以PD更突出,其中Lp(α)、TG、HDL-C变化尤显著,Lp(α)可能是透析病人并发心脑血管事件的危险因素之一.
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