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The relationship between serum homocysteine level and coronary heart disease
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- Author:
- No author available
- Journal Title:
- CHINESE JOURNAL OF PRIMARY MEDICINE AND PHARMACY
- Issue:
- 7
- DOI:
- 10.3760/cma.j.issn.1008-6706.2002.07.005
- Key Word:
- 同型半胱氨酸;叶酸;维生素B12;冠心病
Abstract： 目的探讨血清同型半胱氨酸(Hcy)、叶酸及维生素(Vit)B12水平与冠心病(CHD)的相关性.方法应用荧光微粒子发光法(测定Hcy及VitB12)及离子捕捉法(测定叶酸)检测CHD组(A组)、其它心血管疾病组(B组)和健康对照组(C组)各30例受检者血清Hcy、叶酸、VitB12水平.结果 A组血清Hcy含量明显高于B组(P＜0.01)及C组(P＜0.01);A组血清叶酸含量明显低于B组(P＜0.01)及C组(P＜0.01);A组血清VitB12含量明显低于B组(P＜0.05)及C组(P＜0.05).结论血清Hcy水平的升高与CHD可能有明显的关系.叶酸和VitB12水平的下降与Hcy水平的升高在CHD的发生中可能起着相似的作用.
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